Sarah Sayner, Ph.D.

Sarah Sayner, Ph.D.
Assistant Professor
Phone: (251) 460 6959
Fax: (251) 460 6798
ssayner@usouthal.edu

EDUCATION

1989 B.Sc. (Honors)	University of Northumberland, England
	Environmental Science

1999 Ph.D	Pensacola Junior College, Pensacola, FL
	Undergraduate classes in basic sciences
	University of South Alabama, Mobile, AL

HONORS AND AWARDS

Pensacola Junior College:	President’s list 1998-99
	Leadership award in Biological Sciences Physical Sciences Department Scholar

PROFESSIONAL SOCIETIES

American Physiological Society
Member Phi Theta Kappa Academic Honorary Society

UNIVERSITY SERVICE

University of Northumberland:	Student Representative as member
	of Faculty Review Board 1986-89

Pensacola Junior College:	President of the Biology Club 1998-99
	1998-99 Student tutor in biological sciences

University of South Alabama:	Basic Medical Science Student Organization
	1999-2000 First Year Representative
	2001-2002 President

RESEARCH FUNDING

2003-2005 American Heart association Predoctoral Fellowship Award
Pseudomonas aeruginosa adenylyl cyclase synthesizes cAMP that induces pulmonary microvascular gap formation

PUBLICATIONS

1. Kang H, Sayner SL, Gross KL, Russell LC, Chinkers M. Identification of amino acids in the tetratricopeptide repeat and c-terminal domains of protein phosphatase 5 involved in autoinhibition and lipid activation. Biochemistry 2001 Sep 4;40(35):10485-90

2. Sarah L. Sayner, Dara Frank, Judy King, John VandeWaa, and Troy Stevens Pseudomonas aeruginosa Adenylyl Cyclase (ExoY) Increases cAMP Causing Intercellular Gap Formation in Pulmonary Microvascular Endothelium (in preparation)

3. Sarah Sayner, and Troy Stevens “Regulation of Endothelial cAMP” In Lung Endothelial in Health and Disease, edited by Carolyn E. Patterson (in preparation)

ABSTRACTS

1. Sayner, S.L., Frank, D., VandeWaa, J., Stevens, T., Functional Association of Endogenous Adenylyl Cyclases and Phosphodiesterases in Pulmonary Microvascular Endothelial Cells Revealed by the Expression of Exogenous P. aeruginosa Adenylyl Cyclase, ExoY. FASEB J., 2003
2. Sayner, S.L., Frank, D., VandeWaa, J., Stevens, T., P. aeruginosa Adenylyl Cyclase (ExoY) Increases cAMP Causing Intercellular Gap Formation in Pulmonary Microvascular Endothelium. FASEB J., 2003
3. King, J., Wu, S., Cioffi, D.L., Sayner, S.L., Stevens, T., Inhibition of Type 4 Phosphodiesterase Induces Abluminal Translocation of Endoplasmic Reticulum Tubules in Lung Microvascular Endothelial Cells. FASEB 2003

PRESENTATIONS

1. Center for Lung Biology and Division of Pulmonary and Critical Care Medicine, University of South Alabama, Mobile, AL 2003. “P. aeruginosa exotoxins and virulence: role of adenylyl cyclase, exoY, in lung endothelial permeability.”
2. Experimental Biology, International Convention, San Diego, CA 2003. “P. aeruginosa Adenylyl Cyclase (ExoY) Increases cAMP causing Intercellular Gap Formation in Pulmonary Microvascular Endothelial Cells”.
3. Experimental Biology, International Convention, San Diego, CA 2003. Graduate Student Highlights in Respiratory Physiology “P. aeruginosa Adenylyl Cyclase (ExoY) Increases cAMP causing Intercellular Gap Formation in Pulmonary Microvascular Endothelial Cells”.
4. University of Cambridge, Department of Pharmacology, UK 2003. “ExoY Adenylyl Cyclase of P. aeruginosa generates a phosphodiesterase insensitive cAMP pool and induces pulmonary endothelial gap formation.”